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From Enzyme Adaption to Allosteric Transitions

From Enzyme Adaption to Allosteric Transitions Nobel Lecture

  • Title: From Enzyme Adaption to Allosteric Transitions
  • Author: Jacques Monod
  • ISBN: -
  • Page: 299
  • Format: None
  • Nobel Lecture

    • ☆ From Enzyme Adaption to Allosteric Transitions || ☆ PDF Read by ☆ Jacques Monod
      299 Jacques Monod
    • thumbnail Title: ☆ From Enzyme Adaption to Allosteric Transitions || ☆ PDF Read by ☆ Jacques Monod
      Posted by:Jacques Monod
      Published :2020-08-03T20:22:49+00:00

    About "Jacques Monod"

    1. Jacques Monod

      Jacques Lucien Monod 9 February 1910 31 May 1976 was a French biologist who was awarded a Nobel Prize in Physiology or Medicine in 1965, sharing it with Fran ois Jacob and Andre Lwoff for their discoveries concerning genetic control of enzyme and virus synthesis.Monod along with Fran ois Jacob is famous for his work on the E coli lac operon, which encodes proteins necessary for the transport and breakdown of the sugar lactose lac From their own work and the work of others, he and Jacob came up with a model for how the levels of some proteins in a cell are controlled In their model, the manufacture of proteins, such as the ones encoded within the lac lactose operon, is prevented when a repressor, encoded by a regulatory gene, binds to its operator, a specific site on the DNA next to the genes encoding the proteins It is now known that repressor bound to the operator physically blocks RNA polymerase from binding to the promoter, the site where transcription of the adjacent genes begins.Study of the control of expression of genes in the lac operon provided the first example of a transcriptional regulation system He also suggested the existence of mRNA molecules that link the information encoded in DNA and proteins Monod is widely regarded as one of the founders of molecular biology Monod s interest in the lac operon originated from his doctoral dissertation, for which he studied the growth of bacteria in culture media containing two sugars.Monod was also awarded several other honours and distinctions, among them the L gion d honneur.

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